Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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GLB Brain Sun Cluster Number 36 (744 genes) This page contains all miRNA mediated regulation and functional enrichment for GLB Brain Sun cluster number 36. Information about brain cancer can be found on Wikipedia, and further information about the "GLB Brain Sun" dataset can be found in Sun et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-423-5p Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001505 regulation of neurotransmitter levels 17 GO:0002021 response to dietary excess 4 GO:0003001 generation of a signal involved in cell-cell signaling 33 GO:0003008 system process 107 GO:0006084 acetyl-CoA metabolic process 8 GO:0006171 cAMP biosynthetic process 15 GO:0006810 transport 180 GO:0006811 ion transport 71 GO:0006812 cation transport 52 GO:0006813 potassium ion transport 20 GO:0006836 neurotransmitter transport 19 GO:0007154 cell communication 121 GO:0007186 G-protein coupled receptor protein signaling pathway 43 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 15 GO:0007267 cell-cell signaling 94 GO:0007268 synaptic transmission 75 GO:0007269 neurotransmitter secretion 14 GO:0007399 nervous system development 90 GO:0007610 behavior 38 GO:0007611 learning or memory 18 GO:0007612 learning 10 GO:0007613 memory 9 GO:0007632 visual behavior 8 GO:0008542 visual learning 7 GO:0009187 cyclic nucleotide metabolic process 17 GO:0009190 cyclic nucleotide biosynthetic process 16 GO:0015672 monovalent inorganic cation transport 32 GO:0017157 regulation of exocytosis 9 GO:0019226 transmission of nerve impulse 79 GO:0019233 sensory perception of pain 10 GO:0019933 cAMP-mediated signaling 14 GO:0019935 cyclic-nucleotide-mediated signaling 18 GO:0030001 metal ion transport 49 GO:0030799 regulation of cyclic nucleotide metabolic process 16 GO:0030802 regulation of cyclic nucleotide biosynthetic process 16 GO:0030808 regulation of nucleotide biosynthetic process 16 GO:0030814 regulation of cAMP metabolic process 15 GO:0030817 regulation of cAMP biosynthetic process 15 GO:0031279 regulation of cyclase activity 13 GO:0031644 regulation of neurological system process 20 GO:0032940 secretion by cell 46 GO:0045761 regulation of adenylate cyclase activity 13 GO:0046058 cAMP metabolic process 16 GO:0046903 secretion 49 GO:0048167 regulation of synaptic plasticity 11 GO:0050804 regulation of synaptic transmission 18 GO:0050877 neurological system process 97 GO:0051179 localization 194 GO:0051234 establishment of localization 181 GO:0051339 regulation of lyase activity 13 GO:0051969 regulation of transmission of nerve impulse 19 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-423-5p TargetScan GO:0001505 regulation of neurotransmitter levels 3 17 744 183 0.6348802 hsa-mir-423-5p TargetScan GO:0002021 response to dietary excess 1 4 744 183 0.2546358 hsa-mir-423-5p TargetScan GO:0003001 generation of a signal involved in cell-cell signaling 9 33 744 183 0.2766648 hsa-mir-423-5p TargetScan GO:0003008 system process 31 107 744 183 0.105692 hsa-mir-423-5p TargetScan GO:0006084 acetyl-CoA metabolic process 2 8 744 183 0.3109695 hsa-mir-423-5p TargetScan GO:0006171 cAMP biosynthetic process 6 15 744 183 0.05050025 hsa-mir-423-5p TargetScan GO:0006810 transport 51 180 744 183 0.07662316 hsa-mir-423-5p TargetScan GO:0006811 ion transport 21 71 744 183 0.1222756 hsa-mir-423-5p TargetScan GO:0006812 cation transport 15 52 744 183 0.1815271 hsa-mir-423-5p TargetScan GO:0006813 potassium ion transport 3 20 744 183 0.7659651 hsa-mir-423-5p TargetScan GO:0006836 neurotransmitter transport 4 19 744 183 0.5193653 hsa-mir-423-5p TargetScan GO:0007154 cell communication 35 121 744 183 0.0942483 hsa-mir-423-5p TargetScan GO:0007186 G-protein coupled receptor protein signaling pathway 11 43 744 183 0.3591625 hsa-mir-423-5p TargetScan GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 6 15 744 183 0.05050025 hsa-mir-423-5p TargetScan GO:0007267 cell-cell signaling 29 94 744 183 0.05353025 hsa-mir-423-5p TargetScan GO:0007268 synaptic transmission 22 75 744 183 0.1269103 hsa-mir-423-5p TargetScan GO:0007269 neurotransmitter secretion 3 14 744 183 0.4648914 hsa-mir-423-5p TargetScan GO:0007399 nervous system development 31 90 744 183 0.008715198 hsa-mir-423-5p TargetScan GO:0007610 behavior 9 38 744 183 0.464605 hsa-mir-423-5p TargetScan GO:0007611 learning or memory 5 18 744 183 0.2668705 hsa-mir-423-5p TargetScan GO:0007612 learning 4 10 744 183 0.07214889 hsa-mir-423-5p TargetScan GO:0007613 memory 1 9 744 183 0.6914748 hsa-mir-423-5p TargetScan GO:0007632 visual behavior 4 8 744 183 0.02480954 hsa-mir-423-5p TargetScan GO:0008542 visual learning 4 7 744 183 0.01160348 hsa-mir-423-5p TargetScan GO:0009187 cyclic nucleotide metabolic process 7 17 744 183 0.03503602 hsa-mir-423-5p TargetScan GO:0009190 cyclic nucleotide biosynthetic process 6 16 744 183 0.07159385 hsa-mir-423-5p TargetScan GO:0015672 monovalent inorganic cation transport 7 32 744 183 0.5488454 hsa-mir-423-5p TargetScan GO:0017157 regulation of exocytosis 2 9 744 183 0.3879577 hsa-mir-423-5p TargetScan GO:0019226 transmission of nerve impulse 23 79 744 183 0.1312563 hsa-mir-423-5p TargetScan GO:0019233 sensory perception of pain 4 10 744 183 0.07214889 hsa-mir-423-5p TargetScan GO:0019933 cAMP-mediated signaling 4 14 744 183 0.2451439 hsa-mir-423-5p TargetScan GO:0019935 cyclic-nucleotide-mediated signaling 6 18 744 183 0.1271588 hsa-mir-423-5p TargetScan GO:0030001 metal ion transport 13 49 744 183 0.303142 hsa-mir-423-5p TargetScan GO:0030799 regulation of cyclic nucleotide metabolic process 6 16 744 183 0.07159385 hsa-mir-423-5p TargetScan GO:0030802 regulation of cyclic nucleotide biosynthetic process 6 16 744 183 0.07159385 hsa-mir-423-5p TargetScan GO:0030808 regulation of nucleotide biosynthetic process 6 16 744 183 0.07159385 hsa-mir-423-5p TargetScan GO:0030814 regulation of cAMP metabolic process 6 15 744 183 0.05050025 hsa-mir-423-5p TargetScan GO:0030817 regulation of cAMP biosynthetic process 6 15 744 183 0.05050025 hsa-mir-423-5p TargetScan GO:0031279 regulation of cyclase activity 6 13 744 183 0.02125349 hsa-mir-423-5p TargetScan GO:0031644 regulation of neurological system process 6 20 744 183 0.1989184 hsa-mir-423-5p TargetScan GO:0032940 secretion by cell 9 46 744 183 0.7339452 hsa-mir-423-5p TargetScan GO:0045761 regulation of adenylate cyclase activity 6 13 744 183 0.02125349 hsa-mir-423-5p TargetScan GO:0046058 cAMP metabolic process 7 16 744 183 0.0233799 hsa-mir-423-5p TargetScan GO:0046903 secretion 10 49 744 183 0.6962272 hsa-mir-423-5p TargetScan GO:0048167 regulation of synaptic plasticity 2 11 744 183 0.5332191 hsa-mir-423-5p TargetScan GO:0050804 regulation of synaptic transmission 4 18 744 183 0.4657513 hsa-mir-423-5p TargetScan GO:0050877 neurological system process 29 97 744 183 0.07894204 hsa-mir-423-5p TargetScan GO:0051179 localization 56 194 744 183 0.04554061 hsa-mir-423-5p TargetScan GO:0051234 establishment of localization 51 181 744 183 0.08412988 hsa-mir-423-5p TargetScan GO:0051339 regulation of lyase activity 6 13 744 183 0.02125349 hsa-mir-423-5p TargetScan GO:0051969 regulation of transmission of nerve impulse 5 19 744 183 0.3156319

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